BRD 9876
CAS No. 32703-82-5
BRD 9876 ( BRD9876 )
产品货号. M14062 CAS No. 32703-82-5
BRD 9876 is an ATP- and ADP-competitive Eg5 (kinesin-5) inhibitor with Ki of 4 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
25MG | ¥356 | 有现货 |
|
50MG | ¥518 | 有现货 |
|
100MG | ¥753 | 有现货 |
|
200MG | ¥1102 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称BRD 9876
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述BRD 9876 is an ATP- and ADP-competitive Eg5 (kinesin-5) inhibitor with Ki of 4 nM.
-
产品描述BRD 9876 is an ATP- and ADP-competitive Eg5 (kinesin-5) inhibitor with Ki of 4 nM, selectively inhibits microtubule-bound Eg5 and inhibits multiple myeloma cell growth (IC50=2.2 uM); enhances Eg5-mediated microtubule stabilization.
-
同义词BRD9876
-
通路Cytoskeleton/Cell Adhesion Molecules
-
靶点Kinesin
-
受体Kinesin
-
研究领域——
-
适应症——
化学信息
-
CAS Number32703-82-5
-
分子量234.30
-
分子式C16H14N2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCC(C)(C)C1=CC2=CC(=C(C=C2C=C1)C#N)C#N
-
化学全称6-tert-Butyl-2,3-naphthalenedicarbonitrile
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Chen GY, et al. ACS Chem Biol. 2017 Apr 21;12(4):1038-1046.
2. Chattopadhyay S, et al. Cell Rep. 2015 Feb 4. pii: S2211-1247(15)00030-3.
2. Chattopadhyay S, et al. Cell Rep. 2015 Feb 4. pii: S2211-1247(15)00030-3.
产品手册
关联产品
-
Mps1-IN-2
Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.
-
GSK-1
GSK-1 is an ATP-competitive inhibitor of the mitotic kinesin KSP with HCT116 cell IC50 of 36 nM.
-
SR31527
SR31527 is a novel allosteric Kinesin-like protein KIFC1 inhibitor that inhibits microtubule-stimulated KIFC1 ATPase activity with IC50 of 6.6 uM.